In the High Cost Performance Freeze-drying process, the dried items need to be pre-frozen. The basic purpose of pre-freezing of the product is to immobilize the solid particles in the product during the sublimation of the moisture to prevent physical and chemical reactions of the product. Since liquid products composed of various organic or inorganic materials usually form a eutectic state after pre-freezing, for each product to be freeze-dried, the corresponding eutectic point temperature, that is, the product, should be found. The temperature at which the structural water freezes, and the pre-freezing temperature is also required to be lower than the eutectic point temperature, so that the product is kept in a frozen state, otherwise a product having good properties cannot be obtained. If the pre-freezing temperature is not low enough, the product may not be completely frozen, and it will expand and foam when vacuuming and sublimation; if the pre-freezing temperature is too low, it will not only increase unnecessary energy consumption, but also reduce it for some biological drugs. Survival rate after lyophilization.
In addition, the pre-freezing rate of the product also has a large effect on the drying effect. Rapid cooling is required between the freezing point and the eutectic point temperature of the product, otherwise the living body protein is easily deteriorated. The crystals formed by the crystals are fine and large in rapid cooling. Such ice crystals are slow in sublimation, but dissolve quickly after drying, which can reflect the original structure of the product; the ice crystals produced by slow cooling are large, which is not conducive to sublimation, but dissolves slowly after drying. So, we need to test a suitable cooling rate,
Therefore three data should be determined before pre-freezing. One is the rate of pre-freezing. The rate of pre-freezing should also be different for different products. The second is the minimum temperature for pre-freezing. The minimum temperature for pre-freezing should be lower than the temperature at the eutectic point. The third is the time of pre-freezing. All products are frozen before vacuuming. Don't get out of the bottle due to vacuuming,

Package: strong plywood case, suitable for shipping by sea , by air



 

Options
Vacuum control valve 
Intake backfilling filter
Air inlet filter for pump     
Eutectic point test device       
Electricity heating defrosting
Exhaust filter/oil mist filter for pump
Automatic backfilling / drainage system
Cascade refrigeration ,condenser temperature -80ºC    
Check valve for pump to prevent oil sucked into chamber
Leybold pump or other international brand vacuum pump
External manifold ports to connect round bottom flasks and wide-neck flask
RS232 and software: Check and keep freeze drying data on computer, control freeze dryer through PC
Special requirements can be customized

Main features
*Condenser with uniform and good ice capture function
*Flexible manual and automatic control mode, easy to operate
*With shelf electricity heating function, increasing drying speed
*Shelf temperature can be controlled by program on touch screen
*Safety control system used for shelf heating, to control heating rate
*Color LCD touch screen, display freeze drying curves, save data automatically
*With USB port to output freeze drying data, open and view in Excel format
*Hundreds of recipe can be stored, and each recipe can be set up 36 segments
*Pre-freezing and drying process both finished on shelf, no need to move product
*Inner wall of drying chamber, condenser ,shelf, trays are made of stainless steel 304
*Multilevel password protection for login,effectively prevent illegal operation
*The user level and password can be set up, and the operation management can be divided
*Colorless, transparent acrylic door ,user can observe the whole process of freeze-drying
*With inert gas inflation valve, filling the inert gas after drying can keep products longer
*CFC-free refrigerant, international famous brand compressor, low noise,good efficiency
*Powerful sensor calibration functions to ensure accuracy of measured values in long-term use
*Historical curves and records can be checked, and storage cycles can be modified in real time
*Real-time alarm display, historical alarm query function for fault diagnosis and equipment maintenance

Technical parameters :                         

LGJ-50FD standard type freeze dryer is used for freeze drying experiment in laboratory and small scale production. It is vertical freeze dryer, suitable for drying products in bulk.

This machine has heating shelves and programmable function, Freezing and drying process are finished in the same place.
 

Sichuan University Hunan University 
Qiqihar University
Tianjin University Lanzhou University
 Xiamen University
Tongji University Nanjing University 
Shenyang Pharmaceutical University