Technical parameters :
Freeze drying area | 0.3 |
Shelf size | 400x270 mm |
Shelf number | 3+1 layers (top shelf for heat radiation) |
Shelf spacing | 70 mm |
Tray size | 395x265 mm |
Tray number | 3 pcs |
Condenser temperature | -70ºC |
Shelf temperature | -50~+70ºC |
Bulk capacity | 3 Liter (10mm thickness) |
Final vacuum | <10 Pa |
Vacuum Pump Flow Rate | 4 L/S |
Ice condenser capacity | 6kg /24 hours |
Cooling | Air cooling, ambient temperature≤25ºC |
Vial capacity Φ12mm | 2187 pcs |
Vial capacity Φ16mm | 1200 pcs |
Vial capacity Φ22mm | 654 pcs |
Voltage | 220V/50 Hz, 110V/60Hz, 120V/60Hz |
Power | 3000W |
Defrosting | Electric Defrosting |
Style of press | N/A |
Dimension | 770×750×1520mm |
Weight | 330 kg |
Options:
Data recorder
Vacuum control valve
Intake backfilling filter
Air inlet filter for pump
Eutectic point test device
SS316 material can be used
Electricity heating defrosting
Water cooling refrigeration system
Exhaust filter/oil mist filter for pump
Automatic backfilling / drainage system
Judgement function of freeze-dried end point
Isolation valve between chamber and condenser
Check valve for pump to prevent oil sucked into chamber
Leybold pump or other international brand vacuum pump
External manifold ports to connect round bottom flasks and wide-neck flask
PC and software: Check and keep freeze drying data on computer, control freeze dryer through PC
Special requirements can be customized
Package : plywood case for shipping by sea , by air
The type and function of the control system of the floor type Freeze Dryer are different. For the freeze-drying machine of the experimental series, it is mainly used for the lyophilization process of materials and a small amount of trial production. Therefore, the control system of the Floor Type Freeze Dryer should display the parameters of the freeze-drying process in real time and record automatically; set, modify and effectively execute the freeze-drying process program; and have a communication interface for data collection and storage.
Floor Type Freeze Dryer is suitable for drying high-grade raw materials, Chinese herbal medicines, biological, wild vegetables, dehydrated vegetables, food, fruits, chemicals, pharmaceutical intermediates and other materials. The floor-type freeze-drying machine heat-conducting oil heating system and the dehumidification system are integrated into one, and a new type of box structure is introduced, which utilizes the storage of the material space in the box for drying and vacuum drying.
Floor-standing freeze dryers are processes that remove moisture or other solvents from frozen biological products by sublimation. Sublimation refers to the process of solvents, such as water, like dry ice, which does not pass through a liquid state and changes from a solid to a gaseous state. The product obtained by freeze drying is referred to as a lyophilizer, and the process is referred to as lyophilization. Traditional drying can cause the material to shrink and damage the cells. The structure of the sample is not destroyed during the freeze drying process because the solid component is supported by the firm ice at its location. When the ice sublimes, the floor-type freeze-drying opportunity leaves the pores in the dry remaining material. This preserves the biological and chemical structure of the product and the integrity of its activity. There are many different uses for lyophilization in the laboratory, and floor-standing freeze dryers are indispensable in many biochemical and pharmaceutical applications. Floor-standing freeze dryers are used to obtain biomaterials that can be preserved for long periods of time, such as microbial cultures, enzymes, blood, and pharmaceuticals, retaining their inherent biological activity and structure in addition to long-term storage stability. To this end, lyophilization is used to prepare tissue samples for structural studies (eg, electron microscopy studies). Floor-standing freeze dryers are also used in chemical analysis to obtain dried samples or to concentrate samples to increase analytical sensitivity. Freeze-drying stabilizes the sample composition without changing the chemical composition, which is an ideal analytical aid. Freeze drying can occur naturally. In the natural case, this process is slow and unpredictable. Through the freeze-drying system, people have improved and subdivided many steps to speed up the process.
The refrigeration system of the floor-standing freeze dryer is a compression type refrigeration system consisting of four basic components: a refrigeration compressor, a condenser, an evaporator, and an expansion valve. They are connected by pipelines to form a closed system. The refrigerant circulates continuously in the system, changes state and exchanges heat with compressed air and cooling medium.
Floor Type Freeze Dryer can be dried in a variety of ways, such as drying, boiling, drying, spray drying, and vacuum drying, but common drying methods are usually carried out at temperatures above 0 ° C or higher. The products obtained by the drying of the floor-standing freeze dryer generally have the problems of shrinking volume and hardening of the texture. Most of the volatile components are lost, some heat-sensitive substances are denatured and deactivated, and some substances are even oxidized. Therefore, the dried product has a large difference in properties compared with that before drying. The lyophilization method is basically carried out below 0 ° C, that is, in the state where the product is frozen, and only when the residual moisture content of the product is lowered in the later stage, the product is allowed to rise to a temperature above 0 ° C, but generally does not exceed 40 ° C. Under vacuum conditions, when the water vapor is directly sublimated, the drug remains in the frozen ice shelf, forming a sponge-like porous structure, so the volume after drying is almost constant. Before using it again, as soon as you add water for injection, it will dissolve immediately.
The medicine floor-standing freeze dryer includes two parts: western medicine and traditional Chinese medicine. Western medicine freeze-drying has been developed in China, and many larger pharmaceutical plants have freeze-drying equipment. In terms of injection, the freeze-drying process is used more, which improves the quality and shelf life of the drug, and brings benefits to both doctors and patients. There are not many varieties of freeze-dried medicines, the price of products is high, and the drying process of floor-standing freeze dryers is not advanced. In traditional Chinese medicine, it is limited to the lyophilization of a small amount of Chinese medicinal materials such as ginseng, velvet, yam, and Cordyceps sinensis. A large number of proprietary Chinese medicines have not been freeze-dried, which is far from the foreign countries. Japan launched the "Western Medicine" in a few years ago, which changed the method of tanning of traditional Chinese medicine, solved the tradition that traditional Chinese medicine could not be made into injection or tablet, and solved the problem of Chinese medicine not treating acute illness. Therefore, the Chinese traditional medicine freeze-drying process And product research has great potential to dig.
Floor Type Freeze Dryer technology is mainly used in:
(1) freeze-drying of biological products with poor thermal stability, biochemical products, blood products, genetic engineering products, etc.;
(2) To maintain the structure and activity of biological tissues, the treatment of biological tissues such as cortex, bone, cornea and heart valve for surgery; (3) Coffee to maintain food color, aroma, taste and nutrients, and to quickly rehydrate Freeze-drying of seasonings, meat, seafood, fruits and vegetables;
(4) Application in microcapsule preparation, drug controlled release materials, etc. Processing of health products such as ginseng, royal jelly, and turtles and Chinese herbal preparations to maintain the invariability of fresh substances;
(5) Ultrafine powder functional materials such as: optical fibers, superconducting materials, microwave dielectric materials, magnetic powders, and treatment of catalysts capable of accelerating reaction engineering.